inconsolable
adjective uk/ˌɪn.kənˈsəʊ.lə.bəl/ us/ˌɪn.kənˈsoʊ.lə.bəl/
伤心欲绝的;极度沮丧的;无法慰藉的
so sad or disappointed that it is impossible for anyone to make you feel better
They were inconsolable after the death of their young son. 幼子夭亡后他们伤心欲绝。