downfall
noun [ S ] uk/ˈdaʊn.fɔːl/ us/ˈdaʊn.fɑːl/
衰败；倒台，垮台
(something that causes) the usually sudden destruction of a person, organization, or government and their loss of power, money, or health
Rampant corruption brought about the downfall of the government. 腐败横行导致政府垮台。
In the end, it was the continual drinking that was his downfall. 不断酗酒最终搞垮了他的身体。